The scientific activities encompass bioMEMS research against Cancer – technology development and bio related experiments – as an original interdisciplinary approach to the SIRIC ONCO-Lille program. The projects aims to bridge fundamental and clinical research around 4 work packages related to the scale of transferred biotechnologies:
WP1: Bio molecular mechanisms of the tumor resistance to treatment (DNA degradation under therapeutic irradiations, Microtubules stabilization in chemotherapy, …)
WP2: Cellular evaluation and diagnosis: Stem cells and circulating tumor cells detection and sorting, study of cell senescence and tumor dormancy
WP3: Cells interaction and therapeutic targets: in vitro tumor angiogenesis, cellular mobility and metastatic processes
WP4: Biological adhesives and neo-tissues: cellular fibers and post-surgery recovery.
By means of an upstream research, this program targets more effective disease detection, a strengthened efficacy of therapy and post-treatment monitoring, for a better care to patient.